Computational Modelling Group

Voxel imaging

Voxel (volume elements) imaging essentially encompasses all truly volumetric imaging modalities. Among many other techniques there is particular high interest in voxel imaging using X-ray computed tomography at the School of Engineering Sciences due to the current formation of the µ-VIS (Micro-tomographic Volume Imaging at Southampton) centre.

For queries about this topic, contact Philipp Thurner.

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Projects

Image Based Modelling of Fluid Flow through Lymph Nodes

Tiina Roose, Bharathram Ganapathisubramani, Geraldine Clough (Investigators), Laura Cooper

In this project we are using images of mouse lymph nodes to investigate the fluid transport pathways through it. The images of the nodes are taken using selective plane illumination microscopy, and synchrotron micro computed tomography. The fluid flow is modelled using Darcy's law in COMSOL Multiphysics and the models are run on the Iridis cluster.

Laminar to Turbulent Transition in Hypersonic Flows

Neil Sandham, Heinrich Luedeke

Understanding of laminar to turbulent transition in hypersonic boundary-layer flows is crucial for re-entry vehicle design and optimization. The boundary-layer state directly affects the temperatures on the vehicle surface and its viscous drag. Therefore transition has to be considered to correctly compensate for drag and to properly design the thermal protection system.
For the proposed study, in order to obtain a clear understanding of the transition process, the configuration is kept as simple as possible by varying only a minimum number of parameters affecting transition on a simple test geometry such as a swept ramp at different sweep angles. To investigate the influence of such sweep angles on the transition process in the hypersonic regime, Direct Numerical Simulations (DNS) of the turbulent flow field are carried out on the Iridis cluster.

MXL Project

Mark Taylor, Junfen Shi (Investigators)

‘MXL’ is short for “Enhanced patient safety by computational Modelling from clinically available X-rays to minimise the risk of overload and instability for optimised function and Longevity”. This is an international EU-funded project which the Bioengineering Sciences Research Group at Southampton is involved in. For more information, visit http://www.m-x-l.eu

Prediction of Psychopathology by MRT data

We aim to predict psychopathological outcomes in adults by functional brain data using multilevel regression and crossvaligdation strategies.

Statistical model of the knee

Mark Taylor (Investigator), Francis Galloway, Prasanth Nair

Development of methods for large scale computational testing of a tibial tray incorporating inter-patient variability.

µ-VIS Computed Tomography Centre

Ian Sinclair, Richard Boardman, Dmitry Grinev, Philipp Thurner, Simon Cox, Jeremy Frey, Mark Spearing, Kenji Takeda (Investigators)

A dedicated centre for computed tomography (CT) at Southampton, providing complete support for 3D imaging science, serving Engineering, Biomedical, Environmental and Archaeological Sciences. The centre encompasses five complementary scanning systems supporting resolutions down to 200nm and imaging volumes in excess of one metre: from a matchstick to a tree trunk, from an ant's wing to a gas turbine blade.

People

Geraldine Clough
Professor, Medicine (FM)
Simon Cox
Professor, Engineering Sciences (FEE)
Jeremy Frey
Professor, Chemistry (FNES)
Neil Sandham
Professor, Engineering Sciences (FEE)
Ian Sinclair
Professor, Engineering Sciences (FEE)
Mark Spearing
Professor, Engineering Sciences (FEE)
Mark Taylor
Professor, Engineering Sciences (FEE)
Tiina Roose
Reader, Engineering Sciences (FEE)
Prasanth Nair
Senior Lecturer, Engineering Sciences (FEE)
Fraser Sturt
Senior Lecturer, Humanities (FH)
Philipp Thurner
Lecturer, Engineering Sciences (FEE)
Thomas Blumensath
Senior Research Fellow, Institute of Sound & Vibration Research (FEE)
Richard Boardman
Senior Research Fellow, Engineering Sciences (FEE)
Dmitry Grinev
Research Fellow, Engineering Sciences (FEE)
Heinrich Luedeke
Research Fellow, Engineering Sciences (FEE)
Laura Cooper
Postgraduate Research Student, Engineering Sciences (FEE)
Caroline Duignan
Postgraduate Research Student, Biological Sciences (FNES)
Francis Galloway
Postgraduate Research Student, Engineering Sciences (FEE)
Petrina Butler
Administrative Staff, Research and Innovation Services
Arthur Lugtigheid
Alumnus, Psychology (FSHS)
Kenji Takeda
Alumnus, Engineering Sciences (FEE)
Mohamed Bakoush
None, None
Junfen Shi
None, None