Andrew Collins (Investigator), Jane Gibson, Ioannis Politopoulos
We describe composite likelihood-based analysis of a genome-wide breast cancer case-control sample by determining genome regions of fixed size on a linkage disequilibrium map which delimit comparable levels of linkage disequilibrium. Analysis of findings suggests further validation in more samples from other cohorts as well as the exploitation of novel computationally-intensive methods such as next-generation sequencing.
Using citation network analysis this project aims to investigate the effects that the Cold War had on researchers on both sides of the Iron Curtain.
Marc Molinari, Simon Cox (Investigators), Neil O'Brien
The fast multipole method (FMM) proposed by Greengard and Rokhlin provides a method by which the O(N-squared) many-body problem can be reduced to O(N) complexity. In this project, a multipole method is developed to calculate the energy of a system of vortices in a high temperature superconductor, where the many-body interactions give rise to rich and complex physics. The method developed here is suitable for systems where the interactions are governed by a Bessel potential rather than the usual logarithmic potentials occurring in gravitational and electrostatic problems. We derive and apply vectorised forms of the Gegenbauer addition formulae in order to achieve the O(N) scaling associated with fast multipole methods.
John Shrimpton (Investigator), Gabriel Amine-Eddine
During my final year as an undergraduate, I developed a fully functional software program for visualising geometries, grids and grid quality metrics, for and in-house CFD software tool (HARTREE CFD).
Terence Dawson (Investigator)
As part of a wider project developing a conservation strategy for the marine environment of the Galapagos Islands, this research used multi-variate modelling techniques to develop a habitat suitability prediction model for coral reefs.
Giles Richardson, Roxana-Octavia Carare (Investigators), Alexandra Diem
The observation that solute drainage in the brain occurs in the reverse direction of the blood flow has for a long time been puzzling for researchers. We developed a simple analytical model that can explain this reverse drainage of solutes and has potential implications for the development of treatment for Alzheimer's Disease.
James Dyke (Investigator), Iain Weaver
This work aims to contribute to our understanding of the relationship between complexity and stability. By describing an abstract coupled life-environment model, we are able to employ novel analytical, and computational techniques to shed light on the properties of such a system.
Joanna Nield, Jason Noble, Edward Milton (Investigators), Robin Wilson
Developing methods to monitor the clarity of the atmosphere from satellites at 100,000 times the resolution of previous methods. This can then be used to monitor air pollution, correct satellite images and provide data for climate studies. Simulation is used to model the effects of atmospheric pollution on light passing through the atmosphere, and to test the method under 'synthetic atmospheres'.
Jason Noble, Patrick Doncaster (Investigators), Angela Watkins
A single species spatially-explicit agent-based model has been developed that illustrates the role of simulation modelling, integrated with an adapted least-cost modelling approach and real-world geographical data, in exploring jaguar population dynamics.
A step toward establishing minimum requirement for CFD modelling of dispersion from floating roof tanks
Zheng-Tong Xie, Ian Castro (Investigators)
It is of great importance to estimate an emission flux (due to leaking from an oil tank) from near field wake, which requires a better understanding of vortex shedding from the tank, in particularly in how the low frequency motion behaves. Large-eddy simulation approaches embedded in up-to-date CFD package will be used for this purpose. This project has a strong link with Concawe and U Surrey.