Computational Modelling Group

Microstructural modeling of skin mechanics

Research Team
Emanuele Zappia
Investigators
Georges Limbert

Multi-layer finite element model of a human skin sample (2 mm x 2 mm) subjected to in-plane compression.

The project aims to gain a mechanistic insight into the biomechanics of the skin, particularly around hair follicles via the development of advanced multiscale constitutive equations and micromechanical models integrated into a multiphysics finite element environment. It is planned to implement dedicated constitutive models and also exploit the performance of modern GPU architectures. The project also includes experimental tests to characterise some aspects of the non-linear mechanics of skin components (e.g. epidermis) and also to image the skin microarchitecture via ╬╝CT and/or serial block face scanning.

The project is supported by Procter&Gamble, the largest consumer good company in the world (P&G owns over 35 world-leading brands including Gillette, Braun, Duracell, Pampers, Vicks, Boss, Lacoste and Dolce&Gabbana fragrances). The project includes interactions with P&G R&D teams in the UK and USA.

Categories

Life sciences simulation: Biomathematics, Biomedical, Tissue Engineering

Physical Systems and Engineering simulation: Biomechanics, Elasticity, Materials, Tribology

Algorithms and computational methods: Finite elements, Multi-physics, Multi-scale

Simulation software: Abaqus

Software Engineering Tools: Git, Sublime Text

Programming languages and libraries: Mathematica, Python

Transdisciplinary tags: NGCM, Scientific Computing