Multiscale Modelling of Electrochemical Processes in Neurons
- Started
- 1st September 2010
- Research Team
- Stuart George
- Investigators
- John Chad
A study of how the signalling behaviour of myelinated neurons, such as the speed and frequency at which action potentials can be transmitted, using the method of matched asymptotic expansions, which can be used to account for behaviours down to the nanometre scale. This allows for a mathematical treatment of the limits imposed upon signalling by the effects of ion depletion in extracellular regions in nerve bundles and demyelination in diseases such as Multiple Sclerosis.
Categories
Life sciences simulation: Biomathematics, Neuroscience
Transdisciplinary tags: Complex Systems