Computational Modelling Group

Seminar  10th December 2010 noon  University of Southampton, Building 1, Room 2025

RNASeq applications in genomic research

Dr. Alexander Kanapin
University of Oxford

Web page
http://www.isis.ecs.soton.ac.uk/seminars/?action=viewpresentation&presentation_id=607
Categories
Bioinformatics, Biomathematics, Biomedical, Biomolecular Organisation, Developmental Biology, NextGen Sequencing
Submitter
Richard Edwards

Wellcome Trust Centre for Human Genetics

ISIS = Information: Signals, Images, Systems

Abstract

RNAseq is a recent method developed for next-generation sequencing platforms. RNASeq projects cover a wide range of experiments including differential gene expression, differential splicing, identification of new transcripts/ alternative isoforms, miRNAs, methylation, ChIP-Seq and allele-specific expression. Both experimental methods and statistical tools will be presented and discussed as well as practical examples of different types of the analysis.

Speaker Biography

Dr. Alexander Kanapin, graduate of Moscow University, Russia. PhD in bioinformatics (mobile genetic elements proteins structure analysis). Major projects: InterPro integrated resource of protein functional domains and sites at EBI (key database developer and production manager); major sequencing projects participation human genome, FANTOM (mouse transcriptome). Since 2008 works with Next-Gen sequencing analysis at CSHL, OICR, now at University of Oxford.

Organiser

Professor Mahesan Niranjan

Contact

Tracey Cantlie

Secretary - Information: Signals, Images, Systems (ISIS) Research Group

Electronics and Computer Science

Faculty of Physical and Applied Sciences

University of Southampton

Tel: +44 (0) 23 8059 3813

http://www.isis.ecs.soton.ac.uk/